Staphylococcus Aureus ndi Methicillin-Resistant Staphylococcus Aureus Nucleic Acid

Staphylococcus aureus ndi amodzi mwa mabakiteriya ofunikira amtundu wa nosocomial.Staphylococcus aureus (SA) ndi ya staphylococcus ndipo imayimira mabakiteriya a Gram-positive, omwe amatha kupanga mitundu yambiri ya poizoni ndi ma enzymes owononga.Mabakiteriya ali ndi mawonekedwe a kugawa kwakukulu, mphamvu yamphamvu ya pathogenicity komanso kukana kwakukulu.Thermostable nuclease jini (nuc) ndi jini yotetezedwa kwambiri ya staphylococcus aureus.M'zaka zaposachedwa, chifukwa chogwiritsa ntchito kwambiri mahomoni komanso kukonzekera kwa chitetezo chamthupi komanso kugwiritsa ntchito molakwika maantibayotiki ambiri, matenda a nosocomial omwe amayamba chifukwa cha Methicillin-resistant Staphylococcus aureus (MRSA) ku Staphylococcus akhala akuchulukirachulukira.Avereji yodziwika bwino ya MRSA inali 30.2% mu 2019 ku China.MRSA imagawidwa kukhala MRSA (HA-MRSA), yogwirizana ndi anthu ammudzi (CA-MRSA), ndi MRSA yokhudzana ndi ziweto (LA-MRSA).CA-MRSA, HA-MRSA, LA-MRSA ali ndi kusiyana kwakukulu kwa microbiology, kukana kwa bakiteriya (mwachitsanzo, HA-MRSA imasonyeza kusagwirizana ndi mankhwala ambiri kuposa CA-MRSA) ndi zizindikiro zachipatala (mwachitsanzo, malo opatsirana).Malingana ndi makhalidwe awa, CA-MRSA ndi HA-MRSA akhoza kusiyanitsidwa.Komabe, kusiyana pakati pa CA-MRSA ndi HA-MRSA kukucheperachepera chifukwa cha kuyenda kosalekeza kwa anthu pakati pa zipatala ndi midzi.MRSA imagonjetsedwa ndi mankhwala ambiri, osati kugonjetsedwa ndi maantibayotiki a β-lactam, komanso aminoglycosides, macrolides, tetracyclines ndi quinolones ku madigiri osiyanasiyana.Pali kusiyana kwakukulu m'madera mu chiwerengero cha kukana mankhwala ndi machitidwe osiyanasiyana.

Methicillin resistance mecA jini imagwira ntchito yayikulu pakukana kwa staphylococcal.Jiniyi imatengedwa pamtundu wapadera wamtundu wamtundu wamtundu (SCCmec), womwe umaphatikiza mapuloteni 2a (PBP2a) omwe amamanga penicillin (PBP2a) ndipo amakhala otsika kwambiri ndi ma β-lactam maantibayotiki, kotero kuti mankhwala oletsa tizilombo toyambitsa matenda sangathe kulepheretsa kaphatikizidwe ka cell wall peptidoglycan wosanjikiza, kumabweretsa kusamva mankhwala.