● Mycobacterium Tuberculosis
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Mycobacterium Tuberculosis Nucleic Acid ndi Rifampicin, Isoniazid Resistance
Izi ndizoyenera kuzindikira kwamtundu wa Mycobacterium tuberculosis DNA mu zitsanzo za sputum za anthu mu vitro, komanso kusintha kwa homozygous mu 507-533 amino acid codon region (81bp, rifampicin resistance determining region) ya jini ya rpoB yomwe imayambitsa chifuwa chachikulu cha Mycobacterium. rifampicin kukana.
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Mycobacterium Tuberculosis Isoniazid Resistance Mutation
Chidachi ndi choyenera kuzindikira zamtundu waukulu wa masinthidwe amtundu wa sputum wa anthu omwe amasonkhanitsidwa kuchokera ku Tubercle bacillus positive odwala omwe amatsogolera ku mycobacterium tuberculosis isoniazid kukana: InhA promotioner region -15C>T, -8T>A, -8T>C;Chigawo cholimbikitsa cha AhpC -12C>T, -6G>A;kusintha kwa homozygous kwa KatG 315 codon 315G>A, 315G>C.
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Mycobacterium Tuberculosis Rifampicin Resistance
Chidachi ndi choyenera kuzindikira zakusintha kwa homozygous m'chigawo cha 507-533 amino acid codon cha rpoB gene chomwe chimayambitsa Mycobacterium tuberculosis rifampicin resistance.
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Mycobacterium Tuberculosis Nucleic Acid ndi Rifampicin Resistance
Chidachi ndi choyenera kuzindikira za Mycobacterium tuberculosis DNA mu zitsanzo za sputum za anthu mu vitro, komanso kusintha kwa homozygous m'chigawo cha 507-533 amino acid codon cha jini ya rpoB yomwe imayambitsa kukana kwa Mycobacterium tuberculosis rifampicin.
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Mycobacterium Tuberculosis INH Resistance
Chidachi chimagwiritsidwa ntchito pozindikira kusintha kwa jini kwa 315th amino acid ya jini ya katG (K315G> C) komanso kusintha kwa jini kwa gawo lolimbikitsa la jini ya InhA (- 15 C>T).
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Mycobacterium Tuberculosis DNA
Ndi oyenera kuzindikira Mkhalidwe wa Mycobacterium chifuwa chachikulu DNA mu zitsanzo za anthu matenda sputum, ndipo ndi oyenera matenda wothandiza wa Mycobacterium chifuwa chachikulu matenda.
