Human Cytomegalovirus (HCMV) Nucleic Acid

Human cytomegalovirus (HCMV) ndi membala yemwe ali ndi genome yayikulu kwambiri mubanja la herpes virus ndipo amatha kuyika mapuloteni opitilira 200.HCMV imangokhala pagulu la anthu, ndipo palibe mtundu wa nyama wa matenda ake.HCMV imakhala ndi kubwereza kwapang'onopang'ono komanso kwautali kuti ipange thupi lophatikizika ndi zida zanyukiliya, ndikuyambitsa kupanga matupi ophatikizika a perinuclear ndi cytoplasmic ndi kutupa kwa ma cell (ma cell akulu), chifukwa chake amatchedwa.Malinga ndi kusiyanasiyana kwa ma genome ndi phenotype, HCMV imatha kugawidwa mumitundu yosiyanasiyana, yomwe pali mitundu ina ya antigenic, yomwe, komabe, ilibe tanthauzo lachipatala.

Matenda a HCMV ndi matenda amtundu uliwonse, omwe amakhudza ziwalo zambiri, ali ndi zizindikiro zovuta komanso zosiyana siyana, amakhala chete, ndipo amatha kuchititsa odwala angapo kukhala ndi zotupa zamagulu ambiri kuphatikizapo retinitis, chiwindi, chibayo, encephalitis, colitis, monocytosis, ndi thrombocytopenic. purpura.Matenda a HCMV ndi ofala kwambiri ndipo akuwoneka kuti akufalikira padziko lonse lapansi.Ndilofala kwambiri mwa anthu, ndi chiwerengero cha 45-50% ndi oposa 90% m'mayiko otukuka ndi omwe akutukuka kumene, motero.HCMV imatha kugona m'thupi kwa nthawi yayitali.Pamene chitetezo cha mthupi chafooka, kachilomboka kadzatsegulidwa kuti ayambitse matenda, makamaka matenda obwerezabwereza kwa odwala khansa ya m'magazi ndi kuwaika odwala, ndipo angayambitse limba necrosis ndikuyika moyo wa odwala pangozi.Kuphatikiza pa kubereka, kupititsa padera ndi kubadwa msanga kudzera mu intrauterine matenda, cytomegalovirus ingayambitsenso kubadwa kobadwa nako, kotero kuti matenda a HCMV amatha kukhudza chisamaliro cha usana ndi pambuyo pobereka komanso khalidwe la anthu.